![]() Preventing such severe complications of COVID-19 is the vaccines’s most important role, Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research, said at the October 14 meeting. Like the Pfizer vaccine, Moderna’s mRNA vaccine is holding strong against hospitalizations and deaths from COVID-19. Is Moderna’s jab really becoming less effective over time? Here are answers to five common questions about booster shots. “That is a high bar to which we hold no other vaccines.” What’s more, he added, it may not be reasonable to expect the vaccines to prevent infections and mild illnesses. “People who are in the ICU aren’t there because they haven’t gotten a third dose they haven’t gotten any dose,” Paul Offit, director of vaccine education at the Children’s Hospital of Philadelphia, said at the October 14 advisory panel meeting. Still, experts emphasize that getting shots to unvaccinated people, not boosters to the vaccinated, will make the biggest difference in controlling the pandemic. For instance, people in a clinical trial who got Moderna’s vaccine from August through December 2020 had a 36 percent to 40 percent higher chance of a breakthrough infection than those vaccinated in January through April this year, Jacqueline Miller, therapeutic area head for infectious diseases at Moderna, said at a meeting of the FDA advisory panel considering Moderna’s booster. That panel endorsed both the Moderna and J&J booster during meetings held October 14 and 15. Booster shots may help rev up the immune systems of such vulnerable people, perhaps providing enough protection to stave off the disease’s worst complications.Įven for healthy people, the vaccines’ effectiveness appears to be dipping. Powell, 84, had multiple myeloma, a blood cancer that erodes immune defenses against infections. Joint Chiefs of Staff and secretary of state, died October 18 of complications of COVID-19 even though he was fully vaccinated, his family said in a statement posted on Facebook. Sign up for e-mail updates on the latest coronavirus news and researchĬolin Powell, a former chairman of the U.S. Fully vaccinated people can get COVID-19 and die from it, though at much lower rates than unvaccinated people. ![]() While the vaccines greatly reduce the chance of being hospitalized and dying, there are some chinks in the armor that still leave millions of such people vulnerable to the disease. ![]() These shots may be especially important for older people whose immune systems have weakened with age, and for those with medical conditions that put them at higher risk of serious complications of the disease. Centers for Disease Control and Prevention also gave the thumbs up for boosters for people in those groups. Soon after, CDC director Rochelle Walensky gave the official OK, paving the way for Moderna and J&J shot recipients to join the millions more who received Pfizer’s COVID-19 vaccine and became eligible for boosters in September ( SN: 9/21/21). On October 21, an advisory panel for the U.S. The agency also authorized a second dose of the J&J one-shot vaccine for everyone who got that jab. And FDA said the additional shots could come from any of the authorized or approved vaccines in a mix-and-match strategy. The groups include people age 65 and older as well as 18- to 64-year-olds who have underlying conditions that put them at higher risk for severe disease, or who live or work in conditions that put them at high risk of exposure or complications from falling ill. Food and Drug Administration authorized a third dose of Moderna’s mRNA vaccine for select groups. Millions of people who got Moderna’s or Johnson & Johnson’s COVID-19 vaccines will soon be lining up for another dose.
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